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Program Overview

Profhilo Structura (Reverse Clock Second Generation) is a bio-remodeling treatment based on high-concentration hyaluronic acid, designed to focus on structural-level restoration and reconstruction of the skin. Its primary objective is to address skin laxity and the loss of deep structural support, rather than simply filling volume deficits.

Compared with traditional hyaluronic acid fillers, the second-generation “Reverse Clock” approach places greater emphasis on activating the regenerative mechanisms of collagen and elastin fibers, thereby restoring the skin’s natural firmness and elastic support.

In addition, it provides comprehensive reinforcement of subcutaneous fat-layer architecture and mid-to-lower facial structural support, resulting in gradual and natural improvements. This process helps re-establish the youthful three-dimensional facial contours and stable dermal quality associated with earlier biological states.

Innate Immunity

Innate Immunity

Rapid-response biological defense.

Adaptive Immunity

Adaptive Immunity

Memory and specificity-based defense. T cells (CD8+/CD4+) and B cells (antibody production) are key effectors.

Ideal Candidates

Suitable for individuals experiencing early-stage facial laxity and structural volume loss who prefer a non-filler, non-surgical approach and seek a natural improvement in firmness, elasticity, and skin recoil.

ACCESS

Clinic Information

Eternalab Tokyo

「Cells・Genes・Future」

Address

〒106-0041 1-8-10 Azabudai, Minato-ku, Tokyo Azabu Kaisei Building

Transportation

Tokyo Metro Hibiya LineKamiyacho StationExit 2 7 min walk

Tokyo Metro Namboku LineRoppongi-itchome StationExit 2 10 min walk

Toei Oedo LineAzabu-Juban StationExit 6 12 min walk

Toei Oedo LineAkabanebashi StationNakanohashi Exit 10 min walk

Phone Number

03-5544-9533

Clinic HoursMonTueWedThuFriSatSun
9:00-18:00
Clinic Location Map